Indaziflam is a new herbicide active ingredient, classified as a member of the new chemical class “alkylazine”. There is no published information on its fate and behavior in soil. This study is aimed at characterizing the adsorption and desorption of indaziflam in soils with different physical chemical properties. Three surface soils and three subsurface soils in Minnesota with varying soil properties (pH 5.8-7.6, 1-3% organic carbon, 3-23% clay) were used in the study. Adsorption-desorption studies were performed using the batch equilibration method. Sorption to soil was variable; Kd ranged from 5.7-19.6 mL/g. The surface soils had higher Kf values as compared to the subsurface soils. Normalization of sorption for OC reduced variability, but did not eliminate it. Desorption of indaziflam was hysteretic, indicating that sorption data alone will be not be sufficient to accurately predict its transport in soil. More work is needed to further characterize indaziflam adsorption-desorption in aged soils.