During the past 2.5 years the “open hydroponics” (OH) method of advanced crop production has been intensively studied for proof of concept and adaptation to a new method of growing citrus in Florida. A major incentive for the improved, more efficient citrus production system is the need to remain economically viable despite an increasing incidence of introduced diseases such as citrus greening or Huanglongbing (HLB). The foundation of a successful OH system is based on early, high yields, made possible through 1) high density planting, and 2) accelerated growth from optimal balanced nutrition and water relations achieved with precise computerized fertigation. This paper will discuss the outcomes from 2.5 years of ‘Hamlin’ orange growth in a replicated Central Florida field experiment. Recent results of fruit yield and quality, fertilizer and water use, nitrate-nitrogen leaching, and pest and disease control will be discussed.