An experiment was conducted at Zahak Agriculture Research Station in Iran using factorial design with 3 replications to determine the effects of Zn, Fe and Mn application on yield of wheat and their concentrations in grains in 2003 and 2004. In this experiment Zn with 4 levels (soil application 0, 40 and 80 kg ha-1 and foliar application of 0.5% Znso4 solution), Feso4 with 2 levels (0 and 1%) as foliar application and Mn with 2 levels (0 and 0.5%) also as foliar application were used. Result showed that Zn application significantly increased spike m-2 (p<0.01) and grain yield (p< 0.05) in 2003. Effect of intraction Zn and Mn significantly increased grain spike , weight of 1000 grain (P< 0.05) and grain yield (P<0.01). Analysis result showed that Zn foliar application significantly increasd concentration Zn (P <0.01 ) and concentration Fe in grain (P<0.05) Foliar application Fe increased (P <0.01) concentration Fe and Zn in grain. The Mn foliar application increased Mn concentration in grain. Zn soil application in soils with low Zn concentration increased grain yield. Zn, Fe and Mn concentrations increased in grain with their foliar application. Key words: Wheat, Zn, Fe, Mn, yield, concentration.