Over the past two decades no-till management systems have increased in acres throughout Kansas. No-till has improved soil water conservation while helping reduce soil erosion. The increased amount of available soil water associated with no-till has allowed growers to intensify and diversify their crop rotations. This has resulted in more acres of winter wheat planted following summer row crops. Grain Sorghum (Sorghum bicolor) and winter wheat (Triticum aestivum) are two common crops in Kansas and are adapted to similar growing environments. Previous rotation research has revealed that wheat often performs worse following grain sorghum compared to other summer row crops. The objective of this study was to evaluate various residue and harvest management strategies in no-till systems to improve winter wheat yields following grain sorghum. Three management factors were: glyphosate (preharvest application, postharvest application, and no application), residue (residue removal, residue chopped, and residue left standing), and nitrogen (additional 14 kg ha-1 applied to residue and no additional nitrogen applied). Treatment structure was a 3-way factorial with treatment combinations arranged in a randomized complete block design with four replications. The study was conducted over two years at five locations in Kansas that have environments conducive for planting winter wheat following a summer row crop. Wheat yield components of were evaluated throughout the growing season. For year one, analysis of wheat grain yields resulted in no treatment interactions. At two of the three locations showed significantly higher wheat grain yields when glyphosate was applied to the grain sorghum preharvest. Responses of grain yields to residue treatments were inconsistent across the three locations. These results support the conclusion that residue management and applications of glyphosate can improve fall establishment of winter wheat depending on environment.